The GEA Liquid Processing portfolio of technologies includes the Niro Soavi
VHP Homogenizer Systems which have become the industry standard for particle
size reduction and cell rupture in pharmaceutical and biotech manufacturing. At
the core of the Niro Soavi VHP System is the Niro Soavi homogenizer, renowned
for its robust design, clean-ability, and ease of maintenance.
For biologic cell lysing, the Niro Soavi VHP Homogenizer System offers
distinct advantages over chemical lysing and impinging flow type technologies.
Whereas chemical lysing require additional costly purification and recovery
process steps to yield the desired product, the Niro Soavi VHP system require
no additional processing steps, achieving yields of better than 90% on a single
pass. Unlike cell lysing with impinging flow type equipment, the Niro Soavi VHP
Systems can be easily scaled from the lab and pilot systems through to the
commercial size systems.
Particle size applications for the pharmaceutical industry can be
accomplished at lower pressures than competing technologies because of the high
efficiency sharp profile rupture valve. Components in the VHP system are
constructed of high strength, non-shedding materials so that no unwanted matter
contaminates the product.
With thousands of units installed in production facilities operating
at continuous duties up to 5,000 LPH and 21,750 PSI pressure, the Niro Soavi
VHP Homogenizers and Systems are well proven technology.