Granulation is one of the most important unit operations in the
production of pharmaceutical oral dosage forms. In this article, Niro Pharma
Systems (NPS) introduces different processes, compares them objectively, offers
unbiased advice on the merits of each system, then looks at the implications of
selection on two different applications.
There are a number of
granulation technologies available to pharmaceutical manufacturers. Given the
importance of granulation in the production of oral dosage forms, this paper
offers advice on various process and looks at the implications of two different
applications.
Granulation is one of the most important unit operations
in the production of pharmaceutical oral dosage forms. However, there are many
different technologies each having different strengths and weaknesses. Most
companies choose which one to use simply based on their own experience.This
article introduces different processes, compares them objectively and offers
unbiased advice on the merits of each system. It then looks at the implications
of selection on two different applications.
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By
Harald Stahl
Senior Pharmaceutical Technologist
Niro Pharma Systems
Mauchener Strasse 14, D-79379 Müllheim, Germany
Tel. +49 7631 701 614
Fax +49 7631 701 669
hstahl@niro-pharmasystems.com